Direct (non-stop) flights from New Orleans to Knoxville

MSY Louis Armstrong New Orleans International

New Orleans , LA , USA

TYS Mc Ghee Tyson

Knoxville , TN , USA

CHANGE DIRECTION

Flight time

2h 00m

Flight distance

544mi, 875km

Flights from New Orleans to Knoxville route map

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USA

MSY

New Orleans , LA

USA

TYS

Knoxville , TN

Distance

544 miles · (875 km)

CHANGE DIRECTION

Flight time

2 hours and 00 minutes

Airlines with direct flights from New Orleans (MSY) to Knoxville (TYS)

American Airlines

Oneworld

S

M

T

W

T

F

S

Begins in 2026-11-20

First class available
Southwest Airlines

S

M

T

W

T

F

S

Begins in 2026-11-20

Low-cost airline

FLIGHTS WITH STOPS

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MSY TYS

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MONTHLY

WEEKLY

New Orleans (MSY) to Knoxville (TYS) flight schedule

The monthly calendar shows every direct flight departure from Louis Armstrong New Orleans International (MSY) with all airlines. Click on a date to see a list of flights or search for the best prices.

View return flights from TYS to MSY

American Airlines flight schedule from New Orleans to Knoxville

All weekly departures with American Airlines. The week calendar shows every flight departure from New Orleans (MSY) to Knoxville (TYS). Click on a blue date to see a list of flights.

Week 35 (Aug 24 - Aug 30)

Week 33 (Aug 10 - Aug 16)
Week 34 (Aug 17 - Aug 23)
Week 35 (Aug 24 - Aug 30)
Week 36 (Aug 31 - Sep 6)
Week 37 (Sep 7 - Sep 13)
Week 38 (Sep 14 - Sep 20)
Week 39 (Sep 21 - Sep 27)
Week 40 (Sep 28 - Oct 4)
Week 41 (Oct 5 - Oct 11)
Week 42 (Oct 12 - Oct 18)
Week 43 (Oct 19 - Oct 25)
Week 44 (Oct 26 - Nov 1)
Week 45 (Nov 2 - Nov 8)
Week 46 (Nov 9 - Nov 15)
Week 47 (Nov 16 - Nov 22)

Flight

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Aug 29

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We could not find any flights for this time period. Please try another week.

Southwest Airlines flight schedule from New Orleans to Knoxville

All weekly departures with Southwest Airlines. The week calendar shows every flight departure from New Orleans (MSY) to Knoxville (TYS). Click on a blue date to see a list of flights.

Week 35 (Aug 24 - Aug 30)

Week 33 (Aug 10 - Aug 16)
Week 34 (Aug 17 - Aug 23)
Week 35 (Aug 24 - Aug 30)
Week 36 (Aug 31 - Sep 6)
Week 37 (Sep 7 - Sep 13)
Week 38 (Sep 14 - Sep 20)
Week 39 (Sep 21 - Sep 27)
Week 40 (Sep 28 - Oct 4)
Week 41 (Oct 5 - Oct 11)
Week 42 (Oct 12 - Oct 18)
Week 43 (Oct 19 - Oct 25)
Week 44 (Oct 26 - Nov 1)
Week 45 (Nov 2 - Nov 8)
Week 46 (Nov 9 - Nov 15)
Week 47 (Nov 16 - Nov 22)

Flight

Mon

Aug 24

Tue

Aug 25

Wed

Aug 26

Thu

Aug 27

Fri

Aug 28

Sat

Aug 29

Sun

Aug 30

We could not find any flights for this time period. Please try another week.

Flight time

2h 00m

Route added

March 2026

Flights ending

November 2026

Arriving at Mc Ghee Tyson (TYS) , Tennessee

Mc Ghee Tyson (TYS) is a mid-sized airport based in Knoxville, USA. You can fly to 41 destinations with 7 airlines in scheduled passenger traffic.

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Departing from Louis Armstrong New Orleans (MSY) , Louisiana

Louis Armstrong New Orleans International (MSY) is a bigger airport in USA. You can fly to 56 destinations with 12 airlines in scheduled passenger traffic.

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New Orleans - Knoxville flight price statistics

$590

Approximate

The numbers are avarage prices found based on user searches for direct flights between Louis Armstrong New Orleans International and Mc Ghee Tyson. Its calculated from the cheapest prices found per month for a round-trip with 1 adult and can vary depending on the amount of data we have for this particular route.

N/A
Jan

N/A
Feb

N/A
Mar

N/A
Apr

$915
May

$718
Jun

$398
Jul

$409
Aug

$403
Sep

N/A
Oct

N/A
Nov

N/A
Dec

Approximate prices for one round-trip flight from New Orleans (MSY) to Knoxville (TYS). Graph is not to scale.

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ROUTE EXPLORING

Louis Armstrong New Orleans International - all destinations

With FlightsFrom.com’s brilliant search features you can explore all non-stop flights from a specific airport. Simply select your preferred airport to get an overview of every single non-stop flight offered. Click on one of the routes to get information about which airline’s operate the route, when the next scheduled flight is or to filter your search even more.

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Frequently asked questions FAQ

How long does a flight from New Orleans (MSY) to Knoxville (TYS) take?

The flight between New Orleans (MSY) and Knoxville (TYS) typically takes about 2 hour.
What are the flight numbers on the route New Orleans (MSY) to Knoxville (TYS)?

The flight numbers are AA3622 and WN5103.
Which airports will I be using when flying from New Orleans to Knoxville?

From New Orleans you will fly out from Louis Armstrong New Orleans International (MSY) and you will be landing at Mc Ghee Tyson (TYS).
What aircraft types are flying on this route?

American Airlines and Southwest fly this route with the same aircraft: Embraer 19X/17X.
How many airlines fly non-stop from New Orleans (MSY) to Knoxville (TYS)?

Two airlines. American Airlines and Southwest have non-stop flights to Knoxville.

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MAP EXPLORER Flights from New Orleans to Knoxville route map

Non-stop flights from MSY to TYS

544 miles (875 km) · 2 hours and 00 minutes

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Popular routes from New Orleans

American Airlines routes

New Orleans (MSY) - Dallas (DFW)

New Orleans (MSY) - Charlotte (CLT)

New Orleans (MSY) - Miami (MIA)

New Orleans (MSY) - Washington (DCA)

New Orleans (MSY) - Philadelphia (PHL)

For more destinations from New Orleans with American Airlines (AA), check out the American Airlines route map .

Southwest Airlines routes

New Orleans (MSY) - Dallas (DAL)

New Orleans (MSY) - Houston (HOU)

New Orleans (MSY) - Orlando (MCO)

New Orleans (MSY) - Nashville (BNA)

New Orleans (MSY) - Austin (AUS)

For more destinations from New Orleans with Southwest Airlines (WN), check out the Southwest Airlines route map .

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Airlines with direct flights from New Orleans (MSY) to Knoxville (TYS)

New Orleans (MSY) to Knoxville (TYS) flight schedule

American Airlines flight schedule from New Orleans to Knoxville

Southwest Airlines flight schedule from New Orleans to Knoxville

Arriving at Mc Ghee Tyson (TYS) , Tennessee

Departing from Louis Armstrong New Orleans (MSY) , Louisiana

New Orleans - Knoxville flight price statistics

Louis Armstrong New Orleans International - all destinations

Select your flight details

Frequently asked questions FAQ

Non-stop flights from MSY to TYS

Popular routes from New Orleans

American Airlines routes

Southwest Airlines routes

What is FlightsFrom?

Direct (non-stop) flights from New Orleans to Knoxville

Airlines with direct flights from New Orleans (MSY) to Knoxville (TYS)

New Orleans (MSY) to Knoxville (TYS) flight schedule

American Airlines flight schedule from New Orleans to Knoxville

Southwest Airlines flight schedule from New Orleans to Knoxville

Arriving at Mc Ghee Tyson (TYS) , Tennessee

Departing from Louis Armstrong New Orleans (MSY) , Louisiana

New Orleans - Knoxville flight price statistics

Louis Armstrong New Orleans International - all destinations

Select your flight details

Frequently asked questions FAQ

Non-stop flights from MSY to TYS

Popular routes from New Orleans

American Airlines routes

Southwest Airlines routes

What is FlightsFrom?

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